Nucleotide sequence of bacteriophage phi X174 DNA. 1977 Nature

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Nucleotide sequence of bacteriophage phi X174 DNA.

Sanger F, Air GM, Barrell BG, Brown NL, Coulson AR, Fiddes CA, Hutchison CA, Slocombe PM, Smith M.

Nature. 1977 Feb 24;265(5596):687-95. 


A DNA sequence for the genome of bacteriophage phi X174 of approximately 5,375 nucleotides has been determined using the rapid and simple 'plus and minus' method. The sequence identifies many of the features responsible for the production of the proteins of the nine known genes of the organism, including initiation and termination sites for the proteins and RNAs. Two pairs of genes are coded by the same region of DNA using different reading frames.

PMID: 870828 [PubMed - indexed for MEDLINE]



Genomics Major Paper Publication

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